• List of titles

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List of Titles

Click on the tissue request (TR) number for further details, if available. Please note that only the project titles, follow-up reports and lists of publications arising from the research are available for viewing.

TR1-10       TR11-20       TR21-30       TR31-40       TR41-50       TR51-60

TR1
The project is aiming to assess the differential binding of 11C-PIB and Tritiated PIB on frozen sections of tissue from donors with Parkinson’s Disease with dementia, Alzheimer’s disease and Lewy body dementia.

TR2
The project involves enzymatic analysis of tissue from Parkinson's Disease.

TR3
The project will be comparing gene expression in the substantia nigra of Parkinson's Disease with control tissue, using micro array technology.
This work is funded by the PDS

TR4
The project involves standardisation of alpha-synuclein immunocytochemical staining.

TR5
WP3-1 Tissue Microarray/Quality control block for AD pathology

TR6
Pathways perturbed in Huntington's Disease and related conditions like Parkinson's Disease.

TR7
Toll-like receptors as a repair switch on human glial cells.

TR8
WP3-2 Tissue Microarray/Quality control block for synuclein pathology

TR9
mRNA extraction assessments for fresh snap frozen tissue. To assess the standard of mRNA preservation in the Tissue.

• List of titles

• Reports

• Publications

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TR1-10       TR11-20       TR21-30       TR31-40       TR41-50       TR51-60

TR11
PDS Project grant: gene expression analysis, extension of TR3 investigating histology of tissue sections.

TR12
Sub-cellular localisation of alpha-synuclein.

TR13
An audit of the pathological diagnosis of Inclusion Body Myositis.

TR14
Expression of alpha-synuclein in central myelin in PD.

TR15
Glial activity and convergence of pathological pathways in Lewy Body Parkinsonism.

TR16
Comparison of anti-human alpha synuclein monoclonal antibodies and standardisation of the protocol for the diagnosis of Lewy body diseases.

TR17
Spinal cord pathology in idiopathic Parkinson's Disease.

TR18
Alpha-synuclein in the CNS myelin in Parkinson's Disease.

TR19
Distribution of alpha-synuclein and activated microglia in the parkinsonian substantia nigra.

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TR1-10       TR11-20       TR21-30       TR31-40       TR41-50       TR51-60

TR21
Spatial distribution of neuronal loss in the olfactory bulb of idiopathic Parkinson's.

TR22
Distribution of alpha-synuclein and activated microglia in the parkinsonian substantia nigra.

TR23
Glucocerebrosidase mutations in Parkinson's Disease.

TR24
In situ hybridisation in human post-mortem tissue.

TR25
Comparison of anti-human anti-synuclein antibodies.

TR26
Histopathology of the inferior parietal lobe in PD and DLB.

TR27
Histological clinicopathological survey of PD and the ageing brain.

TR28
In situ measurement of nuclear DNA strand breaks in different cell types and brain regions in Parkinson's disease.

TR29
Regional histopathology of the hippocampus in Parkinson's disease: A role for microglia and astrocytes.

• List of titles

• Reports

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TR1-10       TR11-20       TR21-30       TR31-40       TR41-50       TR51-60

TR31
Distribution of the peripheral benzodiazepine receptor (PBR) in the ageing brain.

TR32
Expression profiling of the Parkinsonian brain using microarrays.

TR33
Expression profiling of the Parkinsonian Brain.

TR34
Fc-gamma receptor expression in PD.

TR35
Microglial activation and pathological protein aggregation in the cortex in synucleinopathies.

TR36
Expression profiling of the Parkinsonian brain.

TR37
Expression profiling of the Parkinsonian brain.

TR38
Expression profiling of the Parkinsonian brain.

TR39
The project involves enzymatic analysis of tissue from Parkinson's disease.

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TR1-10       TR11-20       TR21-30       TR31-40       TR41-50       TR51-60

TR41
The evaluation of 11beta-hydroxysteroid dehydrogenase in human choroid plexus and arachnoid granulation tissue.

TR42
Molecular genetic characterization of Parkinson's disease.

TR43
Histological examination of hypothalamic nuclei in mood and affective disorders.

TR44
Expression profiling of the Parkinsonian brain.

TR45
The role of tau and synuclein in cognitive dysfunction in PD

TR46
CD163 protein expression in human post-mortem tissue.

TR47
A role for alpha-synuclein in neuron and oligodendrocyte degeneration in the spinal cord in MOG-EAE and MS.

TR48
Label-Free screening using photonic crystal sensors for the apoptotic pathway.

TR49
Expression profiling of the Parkinsonian Brain.

• List of titles

• Reports

• Publications

• All details

TR1-10       TR11-20       TR21-30       TR31-40       TR41-50       TR51-60

TR51
Contribution of chromosomal aneuploidy to disease pathology in sporadic Parkinson's disease.

TR52
PDS Programme Grant

TR53
Expression profiling of the Parkinsonian Brain

TR54
Ultrastructural analysis of mitochondria in the CNS of patients with Parkinson`s disease

TR55
Role of activated microglia in neurodegeneration of Parkinson’s disease.

TR56
Pathological correlates of memory loss in multiple sclerosis

TR57
Co-localisation of alpha-synuclein and glial marker proteins in PD/DLB cases

TR58
Assessment of the Braak staging system in UK PDS Tissue Bank

TR59
Study of the mechanisms involved in alpha-synuclein aggregation in alpha-synucleinopathothies.